Crystal structure of human heparanase in complex with heparin tetrasaccharide dp4

Crystal structure of human heparanase in complex with heparin tetrasaccharide dp4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-beta-D-glucopyranose, CHLORIDE ION, ... Authors: Wu, L, Davies, G.J. Deposit date: 2015-10-15 Release date: 2015-11-18 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Structural characterization of human heparanase reveals insights into substrate recognition. Nat.Struct.Mol.Biol., 22, 2015

人乙酰肝素酶（heparanase）与肝素四糖dp4复合物的晶体结构
描述符：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、4-脱氧-2-O-磺基-α-L-苏式-己-4-烯吡喃糖醛酸-(1→4)-2-脱氧-6-O-磺基-2-(磺氨基)-α-D-吡喃葡萄糖-(1→4)-α-L-艾杜糖醛酸-(1→4)-2-脱氧-6-O-磺基-2-(磺氨基)-β-D-吡喃葡萄糖、氯离子（CHLORIDE ION）等
作者：Wu, L、Davies, G.J.
沉积日期：2015-10-15
发布日期：2015-11-18
末次修改日期：2024-11-06
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.73埃（Å）
引用文献：《人乙酰肝素酶的结构表征揭示底物识别机制》，发表于Nat.Struct.Mol.Biol.，2015年，第22卷