Figure S1 - A Dominant Negative Zebrafish Ahr2 Partially Protects Developing Zebrafish from Dioxin Toxicity

In vitro transactivation assays show Ahr21–599 activity. The Cos-7 cell transactivation assay similar to that described in Figure 2 was used to measure the transcriptional activity of different Ahr2 mutants when paired with Arnt2b. Light bars indicate activity in the absence of TCDD; dark bars indicate activity in the presence of TCDD (1 ng/ml). Asterisks indicate activity that is significantly higher than the control cells expressing no Ahr or ARNT, p (EPS)