Jak3

ENCODES a protein that exhibits protein phosphatase binding (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN cytokine-mediated signaling pathway; positive regulation of activated T cell proliferation; positive regulation of calcium ion transport; PARTICIPATES IN altered Jak-Stat signaling pathway; interleukin-2 signaling pathway; interleukin-4 signaling pathway; ASSOCIATED WITH Colonic Neoplasms; Experimental Arthritis; Experimental Autoimmune Encephalomyelitis; FOUND IN extrinsic component of cytoplasmic side of plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A

编码一种表现出蛋白质磷酸酶结合（同源）；蛋白质酪氨酸激酶活性（同源）；参与细胞因子介导的信号通路；正调控激活的T细胞增殖；正调控钙离子转运；参与改变的Jak-Stat信号通路；白细胞介素-2信号通路；白细胞介素-4信号通路；与结肠肿瘤相关；实验性关节炎；实验性自身免疫性脑脊髓炎相关；存在于质膜胞浆侧的外在成分（同源）；与2,3,7,8-四氯二苯并-对-二恶英；苯丙胺；双酚A相互作用。