NCK recruits WASP
收藏reactome.org2025-01-16 收录
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https://reactome.org/PathwayBrowser/#/R-HSA-430180
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The second SH3 domain of NCK interacts with the carboxy-terminal SH3 domain of WASP. WASP family proteins bind the Arp2/3 complex, stimulating its ability to nucleate actin filaments and induce filament branching.
NCK蛋白的第二个SH3结构域与WASP蛋白的羧基端SH3结构域相互作用。WASP家族蛋白与Arp2/3复合物结合,激发其成核形成肌动蛋白丝和诱导肌动蛋白丝分支的能力。
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