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Dysfunction of 5-methylcytosine oxidases and the Polycomb protein RYBP leads to widespread DNA hypermethylation and cell transformation [WGBS]

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP387319
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资源简介:
We inactivated RYBP, YAF2, TET1, TET2, and TET3 in bronchial cells, individually and in combination, and observed widespread DNA methylation by performing whole genome bisulfite sequencing. Overall design: Comparative DNA methylation analysis of WGBS data in HBEC3 defective cell (Control cells, RKO, YKO, TET2 KO, TET3KO, TET2/TET3 DKO, TET123 TKO and TET123/RYBP QKO )
创建时间:
2023-10-07
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