SAE2 belongs to the yeast PRR pathway.
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(A,B) mms2 and rev3 are epistatic to sae2 as judged by a serial dilution assay. (A) sae2 vs. mms2 or rev3. (B) sae2 vs. mms2 rev3. Strains used in (A) and (B) are isogenic derivatives of BY4741. (C) Inactivation of SAE2 partially rescues rad18 sensitivity to DNA damage. Strains used in (C) are HK578-10A (wild type) and its isogenic derivatives WXY2975 (sae2Δ), WXY930 (rad18Δ) and WXY3008 (rad18Δ sae2Δ). Experimental conditions were as described in Figure 1.
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2016-02-23



