Blueprint for modelling time effects in a stepped-wedge, cluster-randomised trial

# Project title

Blueprint for modelling time effects in a stepped-wedge, cluster-randomised trial

# Brief project overview

This is Data coming out of the IPOS-Dem project, a Stepped-wedge Cluster Randomised Trial (SW-CRT). Please make shure to check out the SW-CRT protocol for more details at https://www.doi.org/10.1111/jan.14953.  

We are currently working on our main study (SW-CRT) analysis. While we remain dedicated to open science, our priority is to ensure the utmost integrity of our ongoing research.

# Contributors

Frank Spichiger, Andrea Koppitz, André Meichtry

## Repository overview

|-- readme.md

|-- documentation

  |--readme.md

  |--Datadictionary.html

|-- data

  |--readme.md

  |--IPOS-Dem_CH-SW-CRT_PLD_Qualidem.feather

  |--IPOS-Dem_CH-SW-CRT_PLD_locf_Qualidem.feather

  |--csv

    |--IPOS-Dem_CH-SW-CRT_PLD_Qualidem.csv

    |--IPOS-Dem_CH-SW-CRT_PLD_locf_Qualidem.csv

|-- analysis

  |--readme.md

  |--240229_Analysis_Main.html

  |--240229_Analysis_Main.qmd

  |--grateful-refs.bib

    |--output

      |--models-REML.csv

      |--models.csv

    |--figures

      |--Conversions for plotting - 1.png

      |--Define Model 5-1.png

      |--Defining Model 4-1.png

      |--m1predictions.eps

      |--m1predictions.png

      |--m2predictions.eps

      |--m2predictions.png

      |--m3predictions.eps

      |--m3predictions.png

      |--m4predictions.eps

      |--m4predictions.png

      |--m5predictions.eps

      |--m5predictions.png

      |--Model 1 plot-1.png

      |--Model 1 plot-2.png

      |--Model 2 plot-1.png

      |--Model 2 plot-2.png

      |--Model 3 plot-1.png

      |--More plots for Model 1-1.png

      |--More plots for Model 1-2.png

      |--More plots for Model 4-1.png

      |--More plots for Model 5-1.png

      |--Plots for Model 4-1.png

      |--Plots for Model 5-1.png

      |--Plots for the other two models-1.png

      |--Plots for the other two models-2.png

# Applicable instructions

The R markdown files were generated using R 4.2.2 in RStudio 2023.12.1 for MacOS X you can run them using free software but will need to install R, Rstudio and the packages cited at the end of the quarto or the rendered html we used.

# Additional resources

- Main study protocol: https://www.doi.org/10.1111/jan.14953

- QUALIDEM measure used: https://doi.org/10.1186/1477-7525-11-91 

- Pos-Pal consortium with more information on the measure: https://www.pos-pal.org

- IPOS-Dem translation and adaption: https://www.doi.org/10.1186/s41687-022-00420-7

- IPOS-Dem inter-rating reliability: https://doi.org/10.1371/journal.pone.0286557