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Crystal structure of main protease of SARS-CoV-2 complexed with inhibitor

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Protein Data Bank Japan2026-07-22 更新2026-08-24 收录
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Crystal structure of main protease of SARS-CoV-2 complexed with inhibitor Descriptor: 3C-like proteinase nsp5, N-[(2S)-3-cyclopropyl-1-({(1E,2R)-1-imino-3-[(3R)-2-oxo-2,3-dihydropyridin-3-yl]propan-2-yl}amino)-1-oxopropan-2-yl]-5,7-difluoro-1H-indole-2-carboxamide Authors: Chen, P, Arutyunova, E, Lu, J, Young, H.S, Lemieux, M.J. Deposit date: 2023-09-08 Release date: 2025-03-12 Last modified: 2026-07-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Identification of a Potent Pan-Coronaviral Main Protease Inhibitor J.Med.Chem., 2026

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2023-09-08
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