Changes in H3K27ac following LPS stimulation in pharyngeal epithelial cells

We report changes in H3K27ac following LPS stimulation in Detroit 562 cells. We were able to identified LPS-increased H3K27ac regions which correlated with RELA binding as well as gene up-regulation. This data set is relevant for airborne bacterial sensing as Detroit 562 cells are nasopharyngeal epithelial cells and LPS is a gram negative bacterial endotoxin. Overall design: ChIP-seq for H3K27ac histone mark in Detroit 562 cells under no treatment control condition and after LPS stimulation, each condition in duplicates.