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Preparation and Double Michael Addition Reactions of a Synthetic Equivalent of the Nazarov Reagent

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NIAID Data Ecosystem2026-03-07 收录
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A synthetic equivalent of the Nazarov reagent, the silyl derivative 2, able to undergo base-catalyzed double Michael addition reactions with α,β-unsaturated carbonyl compounds has been developed. The new reagent satisfactorily reacts with unsaturated indolo[2,3-a]quinolizidine lactams to give pentacyclic yohimbinone-type derivatives.

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2013-05-17
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