medication for triple negative breast cancer

NIAID Data Ecosystem2026-03-13 收录

三阴性乳腺癌药物研发

PDE4抑制剂药效评估

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA780375 数据链接链接失效反馈

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资源简介：

explore the effect of the novel phosphodiesterase 4 inhibitor ZL-n-91 on growth in triple-negative breast cancer in vitro and in vivo.

创建时间：

2021-11-15

DataSheet2_Wnt-pathway inhibitors with selective activity against triple-negative breast cancer: From thienopyrimidine to quinazoline inhibitors.docx

三阴性乳腺癌药物研发

Wnt信号通路抑制剂

The Wnt-pathway has a critical role in development and tissue homeostasis and has attracted increased attention to develop anticancer drugs due to its aberrant activation in many cancers. In this stud

NIAID Data Ecosystem50

Discovery of Novel Pyrrolo[2,3‑ d ]pyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors

三阴性乳腺癌药物研发

JAK/HDAC双抑制剂

It remains a big challenge to develop HDAC inhibitors effective for solid tumors. Previous studies have suggested that the feedback activation of JAK-STAT3 pathway represents a key mechanism leading t

NIAID Data Ecosystem30

Table 1 from ZSTK3744, a Novel Aryl Hydrocarbon Receptor Agonist, Exhibits Efficacy against Chemotherapy-Resistant Triple-Negative Breast Cancer

三阴性乳腺癌药物研发

化学结构优化

Structure optimization of ZSTK3341.

NIAID Data Ecosystem10

Exploring Marine-Derived Ascochlorins as Novel Human Dihydroorotate Dehydrogenase Inhibitors for Treatment of Triple-Negative Breast Cancer

三阴性乳腺癌药物研发

DHODH抑制剂

Human dihydroorotate dehydrogenase (hDHODH) is an attractive tumor target essential to de novo pyrimidine biosynthesis. Novel potent hDHODH inhibitors with low toxicity are urgently needed. Herein, we

NIAID Data Ecosystem40

Disease Progression in MRL/lpr Lupus-Prone Mice Is Reduced by NCS 613, a Specific Cyclic Nucleotide Phosphodiesterase Type 4 (PDE4) Inhibitor

系统性红斑狼疮药物研发

PDE4抑制剂药效评估

Systemic lupus erythematosus is a polymorphic and multigenic inflammatory autoimmune disease. Cyclic AMP (cAMP) modulates inflammation and the inhibition of cyclic nucleotide phosphodiesterase type 4

NIAID Data Ecosystem30

medication for triple negative breast cancer

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