Identification and investigation of depression-related molecular subtypes in inflammatory bowel diseases and the anti-inflammatory mechanisms of paroxetine (RNA-seq)
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Effect of Atorvastatin on 5-Fluorouracil Induced Mucositis
5-Fuorouracil (5-Fu) remains one of the most effective and most commonly used drugs to treat colorectal cancer. Mucositis is a major complication that occurs in approximately 80% of patients receiving
NIAID Data Ecosystem50
Candesartan inhibits inflammation through an angiotensin II type 1 receptor independent way in human embryonic kidney epithelial cells
Abstract: Besides stimulating vasoconstriction, Angiotensin II is also well known in inducing reactive oxygen species and promoting inflammatory phenotype switch via its type 1 receptor. In clinic, An
NIAID Data Ecosystem40
Genipin inhibits LPS-induced acute systemic inflammation in mice. Mus musculus
Genipin is a natural blue colorant in food industry. Inflammation is correlated with human disorders, and nuclear factor-κB (NF-κB) is the critical molecule involved in inflammation. In this study, th
NIAID Data Ecosystem30
Glucagon-Like Peptide-1 (GLP-1) Analog Liraglutide Inhibits Endothelial Cell Inflammation through a Calcium and AMPK Dependent Mechanism
Liraglutide is a glucagon-like peptide-1 (GLP-1) mimetic used for the treatment of Type 2 diabetes. Similar to the actions of endogenous GLP-1, liraglutide potentiates the post-prandial release of ins
Figshare2016-01-15 更新40
Amelioration of metabolic syndrome by metformin associates with reduced indices of low- grade inflammation independently of the gut microbiota. Amelioration of metabolic syndrome by metformin associates with reduced indices of low- grade inflammation independently of the gut microbiota
Metformin beneficially impacts several aspects of metabolic syndrome including dysglycemia, obesity and liver dysfunction, thus making it a widely used front line treatment for early-stage type 2 diab
NIAID Data Ecosystem30
