官方服务:
资源简介:
This study proposes to identify the transcriptomic changes associated with degeneration in human nucleus pulposus.
应用场景:
创建时间:
2026-01-24
相关数据集
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
The objective of this study was to compare the expression of the transcriptome in healthy and degenerative intervertebral discs. According to the standard of Pfirrmann Grading, the patients with Pfirr
NIAID Data Ecosystem60
bulk RNA-seq of human nucleusus pulposus from scoliosis patients. bulk RNA-seq of human nucleusus pulposus from scoliosis patients
Intervertebral disc degeneration (IDD) leads to low back pain and disability globally. Progressive loss of nucleus pulposus cells (NPCs) are associated with the onset of IDD. Cell-based therapy has be
NIAID Data Ecosystem40
Next Generation Sequencing analysis at single-cell level of normal and degenerated nucleus pulposus cells transcriptomes
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare NGS-derived retinal transcriptome profiling (RNA-seq) t
NIAID Data Ecosystem60
Conditional deletion of HIF-2α in mouse nucleus pulposus reduces fibrosis and provides mild and transient protection from age-dependent structural changes in intervertebral disc. Conditional deletion of HIF-2α in mouse nucleus pulposus reduces fibrosis and provides mild and transient protection from age-dependent structural changes in intervertebral disc
Hypoxia inducible factors (HIFs) are critical to the development and homeostasis of the intervertebral disc. While HIF-2α, one of the main HIF-α isoforms is expressed in nucleus pulposus (NP) cells, i
NIAID Data Ecosystem30



