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Transcriptome changes in human endothelial cells with reduced cMYC signaling.

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https://www.ncbi.nlm.nih.gov/sra/SRP293274
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资源简介:
Transcriptome profiling of human umbilical vein endothelial cells (HUVECs) transduced with lentiviruses encoding FLAG-CAS9 nuclease and control- (gCTL) or cMYC-targeting (gMYC) gRNAS to identify cMYC regulated genes. Overall design: HUVECs were engineered by CRISPR/CAS9 to ablate cMYC expression. A pool of stable cells for control and MYC-depleted HUVECs was selected after puromycin treatment.
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2025-07-31
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