MECP2 and Associated Rett syndrome pathway WP3584

Figshare2019-02-14 更新2026-04-08 收录

雷特综合征分子通路

发育疾病机制

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https://figshare.com/articles/MECP2_and_Associated_Rett_syndrome_pathway_WP3584/7718564/1 数据链接链接失效反馈

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资源简介：

Pathway from WikiPathways WP3584-97933 - MECP2 and Associated Rett syndrome(Test pathway)<br>

创建时间：

2019-02-14

Transcriptome analysis of Chd8 S62X heterozygote mutant and wild-type mice

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大鼠转录组学

Autism spectrum disorders (ASD) are ~4-times more common in males than females, and CHD8 (a chromatin remodeler)-related ASD shows a strong male bias (~5:1), although the underlying mechanism remains

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Effect of DRP1 mutations on synaptic development during iPSC-derived cortical neuron maturation

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With the advent of exome sequencing, a growing number of children are being identified with de novo loss of function mutations in the large GTPase essential for mitochondrial fission - Dynamin Related

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Single cell transcriptomic analysis of mutant MECP2 human neural cells over a time-course of in vitro differentiation

单细胞转录组学

发育疾病机制

Single cell transcriptomic analysis of mutant MECP2 human neural cells over a time-course of in vitro differentiation

ChEBI2024-11-17 更新20

Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice

发育疾病机制

遗传性侏儒症模型

Ellis-van Creveld (EvC) syndrome is a skeletal dysplasia, characterized by short limbs, postaxial polydactyly, and dental abnormalities. EvC syndrome is also categorized as a ciliopathy because of cil

Figshare2016-12-28 更新30

Additional file 2: of RNA sequencing and proteomics approaches reveal novel deficits in the cortex of Mecp2-deficient mice, a model for Rett syndrome

发育疾病机制

差异表达基因分析

List of significant genes (pÂ <Â 0.05) identified as RTT hits along with references. Information on WT and Mecp2 Jae/y FPKM values, Log2 fold change expression, p-value and q-value (FDR) are provided

Figshare2017-10-25 更新20

MECP2 and Associated Rett syndrome pathway WP3584

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