Single cell transcriptomics of fate-restricted HSCs [scRNAseq HSC]
收藏NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE188118
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HSC subtypes with distintic lineage restriction have been previously reported. Here we examine the single cell transcriptomics of HSC subtypes with P-restricted, PEM-restricted or multilineage in vivo output. Single cell transplantation of Vwf+ HSCs from mouse bone marrow was performed to generated primary recipients showing lineage-restricted reconstitution over 16 weeks: P-restricted, PEM-restricted and multilineage. Donor-derived HSCs were isolated from recipients' bone marrow for single cell RNA-seq, 2 donors for each cell type
创建时间：
2023-02-22
