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Mitochondrial translation requires folate-dependent tRNA methylation

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NIAID Data Ecosystem2026-05-25 收录
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This study investigates the role of folate one-carbon metabolism in mitochondrial physiology. In particular it highlights the need for SHMT2-derived 5,10-methylene-THF to modify mitochondrial tRNAs, which is crucial for mitochondrial translation and therefore oxidative phosphorylation.

创建时间:
2018-02-02
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