Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [NTD-Seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE254796
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To investigate changes in RNAPII distribution in response to SF3B1 mutations, we peformed ChIP-seq using antibody against N-terminal domain of RNAPII (Pan-Pol2) in K562 cells We then performed coverage plot analysis using data obtained from ChIP-seq to investigate RNAPII distribution changes ChIP-seq against NTD-RNAPII in K562 cells across different conditions
创建时间：
2024-06-11
