THYMIDYLATE SYNTHASE TERNARY COMPLEX WITH FDUMP AND METHYLENETETRAHYDROFOLATE
收藏NIAID Data Ecosystem2026-05-02 收录
数据链接:
官方服务:
资源简介:
THYMIDYLATE SYNTHASE TERNARY COMPLEX WITH FDUMP AND METHYLENETETRAHYDROFOLATE
应用场景:
创建时间:
2024-11-06
相关数据集
Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines
G-quadruplexes are higher-order DNA structures formed from guanine-rich sequences, and have been identified as attractive anticancer drug targets. Elucidating the three-dimensional structure of G-quad
NIAID Data Ecosystem60
Crystal Structure of K-Ras WT, GDP-bound
Crystal Structure of K-Ras WT, GDP-bound Descriptor: CALCIUM ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. Deposit date: 2013-07-1
Protein Data Bank Japan2023-09-20 更新40
Challenging the “Undruggable”Targeting STAT3 but Identifying Potent TrkA-Targeted Inhibitors
Signal transducer and activator of transcription 3 (STAT3) is a promising yet challenging anticancer drug target due to its complex signaling and limited “druggability”. To this end, we herein highlig
Figshare2025-04-17 更新30
HUMAN DNA TOPOISOMERASE I IN COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX
HUMAN DNA TOPOISOMERASE I IN COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX Descriptor: 5'-D(*(SPT)P*GP*AP*AP*AP*AP*AP*(5IU)P*(5IU)P*(5IU)P*(5IU)P*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*(5IU)P*(5IU))-3
Protein Data Bank Japan2024-11-06 更新50
Bioorthogonal Profiling of a Cancer Cell Proteome Identifies a Large Set of 3‑Bromopyruvate Targets beyond Glycolysis
3-Bromopyruvate (3BP) is a potential anticancer agent viewed as a glycolytic inhibitor that preferentially kills cancer cells through inhibition of glyceraldehyde 3-phosphate dehydrogenase (GAPDH), re
NIAID Data Ecosystem40



