Pupil size and pupil change correlate with distinct cortical neurochemical systems across the adult lifespan
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De-identified data and analysis code for "Pupil size and pupil change correlate with distinct cortical neurochemical systems across the adult lifespan". This includes per-trial pupillometry, per-subject pupil–BOLD coupling maps in MNI space, group-level stats, and the analysis pipeline. Structural MRI volumes are not publicly shared because they are not defaced. This version features new analyses of brainstem fMRI controlling for physiological noise, making use of the corrected physiological controls from previous version. Artificial intelligence (Claude Code, model Opus 5.5) was used to organize all of the many scripts that produce every number reported in the associated manuscript and check that raw script output matches what is in the manuscript.



