Hemophilia A (HA, OMIM#306700) is an X-linked recessive bleeding disorder caused by the defects in the F8 gene, which encodes coagulation factor VIII (FVIII). Intron 22 inversion (Inv22) is found in a
PhD thesis: PRDM9 Diversity, Recombination Landscapes and Childhood Leukaemia by Ihthisham Ali Appendix III contains hotspot activity analysis data on DNA3 and AA hotspots in a MHCII sub-region. These
This is the first report of a patient with de novo AML carrying the NUP98-PMX1 fusion gene. Next-generation sequencing analysis revealed FMS-like tyrosine kinase-3 (FLT3)-internal tandem duplication (
