Thesis Supplementary Tables
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<b>Supplementary tables for thesis: Deciphering the genetic mechanisms underlying Alzheimer's Disease</b><b>Supplementary Table 2-1: </b>Hi-C cell lines used to create tissue-specific GRNs<b>Supplementary Table 2-2: </b>Two Sample Mendelian Randomisation (2SMR) identifies 179 genes across 9 tissues as causally associated with AD risk<b>Supplementary Table 2-3: </b>2SMR identifies KAT8 as the only gene present across 9 tissues as causally associated with AD risk<b>Supplementary Table 2-4: </b>Location of SNPs tagging sceQTLs in relation to regulating gene which shows diverging tissue AD risk<b>Supplementary Table 3-1:</b><b> </b>Genes included in developmental enrichment analysis based on presence within the Allen Brain Atlas (ABA) RNA-seq datasets<b>Supplementary Table 3-2: </b>Cutoff quantile thresholds of Allen Brain Atlas RNA-seq data for gene set enrichment analysis<b>Supplementary Table 3-3: </b>Full Multimorbid3D pipeline results<b>Supplementary Table 3-4: </b>Multimorbid3D pipeline results of the eight PPINs being investigated<b>Supplementary Table 3-5: </b>KAT8:INO80E IBD/SLE PPIN gene set enrichment analysis results within the Allen Brain Atlas dataset<b>Supplementary Table 3-6: </b>KAT8:INO80E IBD PPIN gene set enrichment analysis results within the gut dataset<b>Supplementary Table 3-7: </b>KAT8:INO80E SLE PPIN gene set enrichment analysis results within the DICE immune cell dataset<b>Supplementary Table 3-8: </b>BIN1 T2DM PPIN gene set enrichment analysis results within the Allen Brain Atlas dataset<b>Supplementary Table 3-9: </b>KAT8 T2DM PPIN gene set enrichment analysis results within the Allen Brain Atlas dataset<b>Supplementary Table 3-10: </b>PLEKHM1 T2DM PPIN gene set enrichment analysis results within the Allen Brain Atlas dataset<b>Supplementary Table 3-11: </b>BIN1, KAT8 and PLEKHM1 T2DM PPIN gene set enrichment analysis results within the pancreas dataset<b>Supplementary Table 3-12: </b>Depression gene set enrichment analysis results within the Allen Brain Atlas dataset
提供机构：
The University of Auckland
创建时间：
2025-07-01
