Summary of the 29 modules that were detected in the yeast data set.

aNumber of genes in each module. bThe chromosome positions of markers associated with each module. cThe most significant GO terms. A total of 510 GO terms of sizes 5 to 300 were tested. Multiple testing corrected (Fisher Exact Test p-value510) p-values less than 0.05 are displayed at four different levels indicated by *. *: 10−3∼0.05; **: 10−5∼10−3; ***: 10−10∼10−5; ****0∼10−10. dNumber of knockout signatures that overlap with each module. 287 knockout signatures [19] were tested and the p-value cut-off is (0.05/287). eNumber of the transcription factors whose binding sites are enriched in each module. 119 transcription factor binding sites [20] were tested and the p-value cut-off is (0.05/119). fOverlapped eQTL hot spots. Multiple testing corrected (Fisher Exact Test p-value13) p-values at cut-off 0.05 are displayed in four different levels indicated by *. gModule 4 is enriched with de novo motifs PAC and RRPE. *10−3∼10−2. **10−5∼10−3. ***10−10∼10−5. ****0∼10−10.