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Microbiota-associated metabolic reprograming influenced clinical outcome in the randomized dendritic cell-based clinical trial in stage III melanoma

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/ERP151271
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Phase III clinical trial (NCT02993315) of the MIND-DC study, in which 148 stage IIIB/IIIC cutaneous melanoma patients were randomized in a 2: 1 ratio to adjuvant treatment with autologous conventional and plasmacytoid mature natural DC (nDC) versus placebo, and serum metabolomics and fecal metagenomics are then analyzed before and after the treatment.
创建时间:
2023-12-31
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