Copy number variation data from iPS cells with PTCHD1-AS deletions. Homo sapiens

iPS cell lines were generated from a male with ASD (proband or prb) and his unaffected mother (control or ctrl). Both individuals carry X-linked 167kb microdeletions that disrupt both PTCHD1 and PTCHD1-AS. We found that cells PTCHD1/PTCHD1-AS-null cells tended to have abnormal karyotypes. Copy number variation analyses were performed to examine genomic stability in control and proband iPS cell lines. Overall design: Genomic DNA from fibroblasts and from two iPS cell lines from each individual were hybridized to the Affymetrix CytoScanHD SNP array