Single cell gene expression profile from wild-type and mutant canine retinas following massively parallel reporter assays using pooled AAV5-promoter-GFP vectors.
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https://www.ncbi.nlm.nih.gov/sra/SRP519597
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资源简介:
Efficacy and specifcity of novel photoreceptor-specific promoters were evaluated in wild-type and mutant (PDE6Ã-RCD1 and RPGR-XLPRA2) dogs at advnced stages of retinal degeneration using massively parallel reporter assays. Overall design: Each dog was injected subretinally with a pool of AAV5-promoter-GFP vectors. Five weeks post-injection, neuroretinal punches were collected and dissociated into single cells for scRNASeq analysis.
创建时间:
2025-07-01



