首页/数据集/Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4DCAF1 in the Nucleus

Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4DCAF1 in the Nucleus

ChEBI2010-03-09 更新2026-07-21 收录

肿瘤抑制机制

泛素化调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-19305 数据链接链接失效反馈

官方服务：

资源简介：

Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4DCAF1 in the Nucleus

应用场景：

创建时间：

2010-03-09

非小细胞肺癌转移

泛素化调控

DDX39B K63-linked ubiquitination mediated by TRIM28 promotes NSCLC metastasis by enhancing ECAD lysosomal degradation

integrated proteome resources100

Common Tumor Suppressive Signaling of Thyroid Hormone Receptor Beta in Breast and Thyroid Cancer Cells

肿瘤抑制机制

转录组学分析

The thyroid hormone receptor beta (TRÃ) is a tumor suppressor in multiple types of solid tumors, most prominently in breast and thyroid cancer. An increased understanding of the molecular mechanisms

NIAID Data Ecosystem90

In vivo FAM134B ubiquitination in AMFR KD cells

泛素化调控

内质网自噬机制

FAM134B is a reticulon-homology domain (RHD)-containing protein that participates in membrane-shaping of the endoplasmic reticulum (ER)8 13. It also functions as a mammalian ER-phagy receptor, mediati

NIAID Data Ecosystem50

Histone chaperone HIRA orchestrates H4K16ac-decorated dynamic chromatin in senescent cells and is required for suppression of oncogene-induced neoplasia.

细胞染色质动态

肿瘤抑制机制

Cellular senescence is a stable proliferation arrest that suppresses tumorigenesis. Histone chaperone HIRA deposits nucleosome-destabilizing histone variant H3.3 into chromatin in a DNA replication-in

NIAID Data Ecosystem90

DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis

DNA损伤修复

泛素化调控

yH2AX immunolocalization is shown for 0.005% MMS-treated U2OS cells stably expressing GFP-Rad18-Ub that were pre-extracted with 0.5% NP-40 in PBS before fixation in PFA.

NIAID Data Ecosystem80

Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4DCAF1 in the Nucleus

资源简介：

相关数据集