Transcriptomic data of downregulated chaperone-mediated autophagy in glioma stem cell activity.
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE181556
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We studied the transcriptomic changes induced by downregulating LAMP2A, key mediator of chaperone-mediated autophagy, in patient-derived glioma stem cells. Overall, 1299 transcripts were significantly downregulated, whereas 1673 appeared to be upregulated. KEGG pathway analysis highlighted PI3K-AKT and p53 signaling and pathways associated with ECM interactions, actin cytoskeleton and focal adhesion as the main altered pathways. Examination of transcriptomic changes induced by chaperone-mediated autophagy downregulation in patient-derived glioma stem cells.
创建时间：
2022-05-02
