BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice
收藏NIAID Data Ecosystem2026-04-25 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP100211
下载链接
链接失效反馈官方服务：
资源简介：
We analyzed the transcriptomic changes and Brd4 global occupancy in Th17 cells treated with JQ1 and MS402. We find that MS402 selectively targets Th17 cells and displaces Brd4 occupancy at Th17-selective genes. Overall design: RNA-seq samples were analyzed from Th17 cells treated with JQ1 and MS402. ChIP-seq samples were analyzed to determine global Brd4 occupancy in response to MS402 treatement.
创建时间：
2019-09-28
