File S1 - NbIT - A New Information Theory-Based Analysis of Allosteric Mechanisms Reveals Residues that Underlie Function in the Leucine Transporter LeuT

Supporting Methods (MD simulations; Moving block bootstrapping of MD simulations; Contributions for specific information measures; Identifying high information residues); Supporting Discussion (Efficient information transmission; Normalizing mutual information; Negative co-information; Analysis of the K1,4 network; Control study); Tables S1–S4; Figures S1–S11; Supporting References. (PDF)