Inhibition of p38 MAPK in DC progenitor cells endows DCs with superior immunogenicity

ChEBI2014-05-22 更新2026-07-21 收录

树突状细胞免疫调控

p38 MAPK信号通路

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-57879 数据链接链接失效反馈

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Inhibition of p38 MAPK in DC progenitor cells endows DCs with superior immunogenicity

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2014-05-22

PTBP1 is necessary for dendritic cells to regulate T cells homeostasis and antitumor immunity

树突状细胞免疫调控

肿瘤免疫治疗靶点

Dendritic cells (DCs) play an important role in innate and adaptive immunity. DCs could sense environment pathogens and tumors, presenting those antigens to T cells. PTBP1, an RNA-binding protein, the

NIAID Data Ecosystem60

Analysis of PMK-1 p38 MAPK and PMK-1(D327E) Caspase Cleavage Resistant Mutant and Effect of DAF-16 (FOXO) Mutants on Gene Regulation in C. elegans

线虫基因调控网络

p38 MAPK信号通路

We identified genes inversely regulated by pmk-1 null mutation and pmk-1(D327E). We also identified genes working through daf-16, working around daf-16 and working independent of daf-16 Overall design

NIAID Data Ecosystem20

A Caenorhabditis elegans gene-environment atlas reveals p38 MAPK as a reservoir of phenotypic plasticity in cellular regulation

秀丽隐杆线虫基因研究

p38 MAPK信号通路

[ID, Bait, Tissue, Age, Label Time (hr), Stress, Group, Rep] [988452, GFP, Whole Body (eft-3p), L1-L3, 20, No, early larval, 1] [988453, PMK-1, Whole Body (eft-3p), L1-L3, 20, No, early larval, 1] [99

NIAID Data Ecosystem10

GNPS - Lipidomics of dendritic cells treated with adjuvant

脂质组学

树突状细胞免疫调控

Discovery lipidomics was performed on media (+/- Adjuvant) and cultured dendritic cells (+/- Adjuvant or LPS). Samples were from two growth batches, and in each batch there were n=3 for each cell cond

NIAID Data Ecosystem20

Impact of Leishmania mexicana Infection on Dendritic Cell Signaling and Functions

寄生虫免疫

树突状细胞免疫调控

Leishmania parasites have the ability to modify macrophage signaling pathways in order to survive and multiply within its mammalian host. They are also known to invade other cells including neutrophil

Figshare2016-01-15 更新10

Inhibition of p38 MAPK in DC progenitor cells endows DCs with superior immunogenicity

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