five

Recyclable Polymer Supported DMAP Catalyzed Cascade Synthesis of α‑Pyrones

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NIAID Data Ecosystem2026-05-01 收录
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https://figshare.com/articles/dataset/Recyclable_Polymer_Supported_DMAP_Catalyzed_Cascade_Synthesis_of_Pyrones/23694609
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Polymer-supported catalysts have emerged as one of the sustainable and cost-effective alternatives in organic synthetic chemistry. We have developed the first polymer-supported DMAP catalyzed one-pot synthesis of diversely substituted α-pyrones. The cascade approach involves C5 conjugate addition of 5H-oxazol-4-ones to α,β-unsaturated-β-ketoesters followed by lactonization/elimination.
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2023-07-17
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