The mechanisms that contribute to the maintenance of serological memory are still unclear. Rotavirus (RV) memory B cells (mBc) are enriched in IgM+ and CD27- subpopulations, which are associated with

Figshare2016-01-18 更新50

Expansion of an FCRL5+ B cell subset resembling atypical memory B cells in an animal model of malaria

疟疾免疫反应

B细胞亚群功能

Background: In human malaria, parasites of the genus Plasmodium elicit expansion of atypical memory B cells (atMBCs), which lack the classical markers CD21 and CD27. We have identified a putative popu

NIAID Data Ecosystem30

Expression profiling of hemocytes from Anopheles gambiae after malaria parasite infection. Anopheles gambiae

疟疾免疫反应

蚊虫基因表达

Insect hemocytes mediate important cellular immune responses including phagocytosis and encapsulation, and also secrete immune factors such as opsonins, melanization factors, and antimicrobial peptide

NIAID Data Ecosystem60

Implication of TIGIT+ human memory B cells in immune regulation

免疫调控机制

记忆B细胞

Regulatory B cells (Bregs) contribute to immune regulation. However, the mechanisms of action of Bregs remain elusive. Here, we report that T cell immunoreceptor with Ig and ITIM domains (TIGIT) expre

NIAID Data Ecosystem40

FCRL5 delineates functionally impaired memory B cells associated with malaria exposure

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