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Control of Embryonic Brown Adipocyte Development by GATA6 II

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Brown adipose tissue (BAT) is a thermogenic organ that protects animals against hypothermia and obesity. BAT derives from the multipotent paraxial mesoderm; however, the identity of embryonic brown fat progenitor cells and regulators of adipogenic commitment are unclear. Here, we performed single cell gene expression analyses of mesenchymal cells during mouse embryogenesis with a focus on BAT development. Live (DAPI(-)) cells from control and Gata6deltaMyf5 mutant embryos harvested at E14.5

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