File S1 - A Robust Model-free Approach for Rare Variants Association Studies Incorporating Gene-Gene and Gene-Environmental Interactions
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The supporting information file for article “A Robust Model-free Approach for Rare Variants Association Studies Incorporating Gene-Gene and Gene-Environmental Interactions”. It contains the files: Table S1. Models to generate simulated phenotypes; Table S2. Power of different methods for dichotomous traits in scenarios 1∼6 (α = 0.05); Table S3. Power of different methods for dichotomous traits in scenarios 1∼6 (α = 0.01); Table S4. Power of different methods for continuous traits in scenarios 1∼6 (α = 0.05); Table S5. Power of different methods for continuous traits in scenarios 1∼6 (α = 0.01); Table S6. Power of different methods for dichotomous traits in G×E interaction effect models (α = 0.05); Figure S1: Type I error for different methods in various sample sizes with nominal α levels 0.05 (left) and 0.01(right); Figure S2: Power comparison in scenarios 1∼6 for dichotomous traits with 500 cases and 500 controls when the SNP number is 30. (DOC)



