IL13 and CCL2 Drive Disease in an Inflammatory Subset of Scleroderma [cGVHD]

ChEBI2011-06-30 更新2026-07-21 收录

皮肤炎症机制

细胞因子作用机制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-17914 数据链接链接失效反馈

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IL13 and CCL2 Drive Disease in an Inflammatory Subset of Scleroderma [cGVHD]

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2011-06-30

cFLIP prevents TNFR1-dependent lethal dermatitis and TNFR1-independent blockade of epidermal differentiation

皮肤炎症机制

表皮分化调控

Cellular FLICE-inhibitory protein (cFLIP) prevents the development of dermatitis by blocking TNFα-dependent apoptosis of keratinocytes. However, it is unclear whether TNFα-independent signal might als

NIAID Data Ecosystem100

IL-17A and IL-22 synergistically stimulated human epithelial cells inducing IL-8.

细胞因子作用机制

免疫信号通路

(A) IL-8 production at 24 hours by AGS cells in response to IL-22 and IL-17A as measured by ELISA. p-value is based on ANOVA test with Dunnett’s correction for multiple comparisons ***p

Figshare2016-03-16 更新50

Comparing transcriptional profiles of skin biopsies from healthy controls and subjects with chronic pruritus of unknown origin and atopic dermatitis

皮肤转录组学

皮肤炎症机制

Type 2 inflammation contributes to the pathology of pruritic skin diseases such as atopic dermatitis (AD). Chronic pruritus of unknown origin (CPUO) is a skin condition of unknown etiology that typica

NIAID Data Ecosystem40

NGS5522 - hMDMS response to IFNg and TNFa

免疫细胞响应

细胞因子作用机制

human primay macrophages (hMDMs) were unstimulated, stimulated with IFNg or costimulated with IFNg and TNFa for 18h Overall design: human primay macrophages (hMDMs) were unstimulated, stimulated wi

NIAID Data Ecosystem50

Data_Sheet_2_Circulating Cytokines and Coronavirus Disease: A Bi-Directional Mendelian Randomization Study.pdf

COVID-19免疫研究

细胞因子作用机制

BackgroundImmune system functioning is relevant to vulnerability to coronavirus disease (COVID-19). Cytokines are important to immunity. To further elucidate the role of the immune system in COVID-19,

NIAID Data Ecosystem40

IL13 and CCL2 Drive Disease in an Inflammatory Subset of Scleroderma [cGVHD]

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