Anatomy of the left ventricle in fibrotic non-ischaemic dilated cardiomyopathy (NIDCM)

Supporting data for the study titled "Left Ventricular Shape Predicts Arrhythmic Risk in Fibrotic Dilated Cardiomyopathy" published in Europace (https://doi.org/10.1093/europace/euab306) Collection of 156 computational meshes of the anatomy of the left ventricle of 156 subjects with fibrotic NIDCM Data acquisition and segmentation Original Late Gadolinium Enganced (LGE-CMR) images originate from a cohort of 157 patients enrolled in the Royal Brompton Hospital Cardiovascular Biobank Project. Short axis LGE-CMR images stacks were acquired with an acquired scanning resolution of 1.3-2.2mm in plane and with a 7-10.5mm slice thickness. LGE-CMR stacks were manually segmented. An additional point was marked, the most basal point of the RV epicardium that meets the liver, required to break the circumferential symmetry of the LV in the ventricular shape models, and providing a marker for the most basal slice (images above this slice were removed). 3D meshingThe LV end diastolic anatomy was reconstructed from the short axis image contours using high order interpolation meshes. An idealised ellipsoid (with 96 elements, 194 nodes and 4656 degrees of freedom) was tailored to the dimensions of each case, and image registration and mesh warping techniques used to fit an idealised ellipsoid to each patient’s contours. High-order interpolation basis functions (cubic Hermite) in the meshes were used to interpolate the typically sparse out of plane resolutions in the short axis acquisitions. The 156 meshes were then spatially aligned by their centres of mass, and oriented by their basal planes and manually marked points at the RV epicardium. Data shared contains:1. AtlasMeshData.zip, where each case has 1.1 IDseg.nii: The mask (segmentation) of the left ventricular (LV) myocardium and right ventricular blood pool from the short axis magnetic resonance image in end diastole. NIFTI format.1.2 IDseg_mesh files: the degrees of freedom of the cubic Hermite mesh that was personalised to the anatomy of the left ventricle1.3 Image_IDseg_mesh.jpg: image of the overlay between the fitted mesh and the mask of the LV myocardium1.4 Image_Initialization.jpg: image of the overlay between the template LV mesh used for personalization and the mask of the LV myocardium1.5 ImageDistances2ClosestPointIDseg_meshxxxxxxxxxx.jpg: image of the distances between the LV mesh and the mask of the LV myocardium (xxxxxxxxxx is a digit encodign for the time when the image was generated)1.6 PersonalizationReportbinary.txt: file with metrics of mesh fitting accuracy and quality1.7 GeoReport.txt: file with the collection of most prevalent geometrical descriptors of the left ventricle, 1.8 CurvatureMetrics.mat, GeometricalMetrics.mat and ThicknessMetrics.mat: matlab files with a comprehensive collection of descriptors of the left ventricle. 2. VTKMeshes.zip: the collection of all the LV shapes in VTK format, after correction of centre of mass and circumferential orientation.本数据集为发表于《Europace》（DOI: 10.1093/europace/euab306）的题为《左心室形态预测纤维化扩张型心肌病心律失常风险》的研究配套支持数据。 本数据集包含156例纤维化NIDCM受试者的左心室解剖学计算网格，合计156套。 数据采集与分割： 原始延迟钆增强磁共振（Late Gadolinium Enhanced, LGE-CMR）图像来自皇家布朗普顿医院心血管生物库项目招募的157例患者队列。短轴位LGE-CMR序列图像的平面内扫描分辨率为1.3~2.2mm，层厚为7~10.5mm。所有LGE-CMR序列图像均经手动分割。额外标记了右心室心外膜与肝脏毗邻的最基底点位，该点位可用于打破心室形态模型中左心室的周向对称性，并作为最基底层面的定位标记——该层面以上的图像将被移除。 三维网格构建： 采用高阶插值网格，基于短轴位图像轮廓重建左心室舒张末期解剖结构。针对每个病例定制了包含96个单元、194个节点及4656个自由度的理想化椭球网格，并通过图像配准与网格变形技术，将该理想化椭球拟合至每位患者的图像轮廓。网格中采用三次埃尔米特（cubic Hermite）高阶插值基函数，以弥补短轴位采集时平面外分辨率不足的问题。随后将156套网格通过质心完成空间对齐，并以基底平面及手动标记的右心室心外膜点位完成定向。 共享数据内容： 本次共享的数据包含： 1. AtlasMeshData.zip：每套病例包含以下文件： 1.1 IDseg.nii：舒张末期短轴位磁共振图像中左心室心肌与右心室血池的掩码（分割结果），格式为NIFTI。 1.2 IDseg_mesh文件：针对每位受试者左心室解剖个性化定制的三次埃尔米特网格自由度数据。 1.3 Image_IDseg_mesh.jpg：拟合网格与左心室心肌掩码的叠加效果图。 1.4 Image_Initialization.jpg：用于个性化拟合的模板左心室网格与左心室心肌掩码的叠加效果图。 1.5 ImageDistances2ClosestPointIDseg_meshxxxxxxxxxx.jpg：左心室网格与左心室心肌掩码之间的距离映射图（xxxxxxxxxx为图像生成时的时间编码数字）。 1.6 PersonalizationReportbinary.txt：包含网格拟合精度与质量评估指标的文本文件。 1.7 GeoReport.txt：包含左心室最具代表性几何描述符的汇总文件。 1.8 CurvatureMetrics.mat、GeometricalMetrics.mat及ThicknessMetrics.mat：包含左心室各类描述符综合集合的MATLAB数据文件。 2. VTKMeshes.zip：包含所有经质心校正与周向定向校正后的左心室形态的VTK格式网格集合。