In vivo intracellular electrophysiology: midline thalamus, medial prefrontal cortex

This data set includes intracellular recordings, obtained from the midline thalamus and the mPFC of mice under ketamine-xylazine anesthesi. Intracellular recordings were obtained together with local field potential recordings of the hippocampus (CA1), mPFC, thalamus and a respiration signal measured by piezoelectric sensors placed around the thorax.
In the midline thalamus, we observed EPSPs and action potentials, phase-locked to respiration and prefrontal gamma packets (30-80 Hz). In contrast, the main contributor to prefrontal synaptic activity was the slow oscillation with little to no modulation resulting from respiration.

本数据集收录了由小鼠中线丘脑和中皮层前额叶皮层在甲烷-氯胺酮麻醉下获得的细胞内记录。细胞内记录与海马（CA1）、皮层前额叶、丘脑以及置于胸部周围的压电传感器测量的呼吸信号相伴随的局部场电位记录相结合。在中线丘脑中，我们观察到了与呼吸和前额叶伽马包（30-80赫兹）相位锁定的兴奋性突触后电位（EPSPs）和动作电位。相反，皮层前额叶突触活动的主要贡献者是缓慢振荡，其呼吸调节的影响微乎其微。