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Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: mechanisms and pitfalls

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Immunology Database and Analysis Portal2025-10-30 更新2026-07-12 收录
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We uncovered shortcomings when using certain antibodies that target Siglec-F to deplete mouse eosinophils, while administration of anti-Siglec-8 antibody to Siglec-8 transgenic mice works well.

提供机构:
ImmPort
创建时间:
2020-07-31
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