Active miRs identified in the miR-155 dataset.

aThe sign of the p-value marks the direction of the response of the miR target set: positive and negative p-values correspond to miRs whose target sets are significantly up- and down-regulated in miR-deficient Th2 cells, respectively, compared to wild type Th2 cells. The results obtained for the true signal in this dataset��miR-155��are emphasized in bold-italic font, and are in the expected direction: that is, the set of miR-155 predicted target genes is up-regulated in miR-155 deficient Th2 cells compared to control Th2 cells.bBest p-value obtained for 20 randomly permuted seeds derived from the original one.