Crystal structure of the PI5P4Kbeta-ITP complex
收藏Protein Data Bank Japan2023-11-29 更新2026-03-21 收录
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Crystal structure of the PI5P4Kbeta-ITP complex Descriptor: INOSINE-5'-DIPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta, [[(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-(6-oxidanylidene-1~{H}-purin-9-yl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate Authors: Senda, M, Senda, T. Deposit date: 2021-04-13 Release date: 2022-03-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.65 Å) Cite: The GTP responsiveness of PI5P4K beta evolved from a compromised trade-off between activity and specificity. Structure, 30, 2022
PI5P4Kβ-ITP复合物的晶体结构
描述符:肌苷-5'-二磷酸(Inosine-5'-Diphosphate)、磷脂酰肌醇5-磷酸4-激酶2型β(Phosphatidylinositol 5-phosphate 4-kinase type-2 beta)、[[(2R,3S,4R,5R)-3,4-二羟基-5-(6-氧代-1H-嘌呤-9-基)四氢呋喃-2-基]甲氧基-氧代磷酰基]膦酸氢酯
作者:Senda M、Senda T
存入日期:2021-04-13
发布日期:2022-03-30
最后修改日期:2023-11-29
实验方法:X射线衍射(分辨率2.65 Å)
引用:PI5P4Kβ的GTP响应性源自活性与特异性间的失衡权衡。《Structure》,第30卷,2022年
创建时间:
2021-04-13



