BindingDB Entry 50018703: Discovery of tricyclic dipyrrolopyridine derivatives as novel JAK inhibitors.

Small molecule binding data for protein Angiopoietin-1 receptor, Aurora kinase C, Bone morphogenetic protein receptor type-1A, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Casein kinase I isoform delta, Cyclin-dependent kinase 2, Dual specificity mitogen-activated protein kinase kinase 1, Ephrin type-A receptor 2, Epidermal growth factor receptor, Focal adhesion kinase 1, Glycogen synthase kinase-3 beta, High affinity nerve growth factor receptor, Inhibitor of nuclear factor kappa-B kinase subunit beta, Insulin-like growth factor 1 receptor, MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 11, Mitogen-activated protein kinase 8, Mitogen-activated protein kinase kinase kinase 1, Proto-oncogene tyrosine-protein kinase Src, RAC-alpha serine/threonine-protein kinase, RAF proto-oncogene serine/threonine-protein kinase, Ribosomal protein S6 kinase beta-1, Serine/threonine-protein kinase Chk1, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BTK, Tyrosine-protein kinase CSK, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase JAK3, and Tyrosine-protein kinase ZAP-70, Uniprot O14757, O14920, O60674, P00519, P00533, P04049, P04629, P08069, P12931, P23443, P23458, P24941, P29317, P31749, P36894, P41240, P43403, P45983, P48730, P49137, P49841, P52333, Q02750, Q02763, Q05397, Q06187, Q08881, Q13233, Q15759, Q9UQB9, and Q9UQM7