A M. tuberculosis transposon library was used to infect WT and iNOS-/- mice. Surviving mutants were recovered from spleens, genomic DNA was extracted, and labeled probes were synthesized from transpo
1This infectivity is calibrated such that one index case creates on average 1.3 secondary cases in a population of 1000 healthy susceptibles and conforms to Blower (2004) [36]. 2Fitness is a multiplie