Dihydrofolate Reductase (DHFR) of Aspergillus flavus in complex with a small molecule inhibitor
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Dihydrofolate Reductase (DHFR) of Aspergillus flavus in complex with a small molecule inhibitor Descriptor: 3-{[(3R)-7,9-diamino-3-methyl-2,3-dihydrofuro[2,3-f]quinazolin-4-yl]oxy}benzonitrile, Dihydrofolate reductase, putative, ... Authors: Bensen, D.C, Fortier, J.M, Akers-Rodriguez, S, Tari, L.W. Deposit date: 2018-06-12 Release date: 2019-06-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.997 Å) Cite: Prospecting for broad-spectrum inhibitors of fungal dihydrofolate reductase using a structure guided approach. To Be Published
黄曲霉(Aspergillus flavus)的二氢叶酸还原酶(Dihydrofolate Reductase,DHFR)与小分子抑制剂所形成的复合物。描述项:3-{[(3R)-7,9-二氨基-3-甲基-2,3-二氢呋喃并[2,3-f]喹唑啉-4-基]氧基}苯甲腈、推定二氢叶酸还原酶…… 作者:Bensen D.C.、Fortier J.M.、Akers-Rodriguez S.、Tari L.W. 存储日期:2018年6月12日,发布日期:2019年6月19日,最后修改日期:2023年10月11日。实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.997埃。引用文献:《采用结构导向策略筛选真菌二氢叶酸还原酶广谱抑制剂》(待发表)
创建时间:
2018-06-12



