Raw Data Supporting the Study "Circulating PIEZO1 Levels in Complex Regional Pain Syndrome Type 1 and Their Association with Time from Neridronate Treatment"

This dataset contains the anonymized raw data underlying the analyses presented in the associated manuscript investigating circulating PIEZO1 serum levels in patients affected by Complex Regional Pain Syndrome type 1 (CRPS-1). The dataset includes demographic, clinical, and laboratory variables collected from CRPS-1 patients and healthy controls. Variables comprise subject identification codes, sex, age, treatment-related timing, clinical response classification, pain-related scores, and circulating PIEZO1 concentrations measured in serum samples. For a subgroup of patients, paired longitudinal data collected before and after neridronate treatment are also included, allowing intra-individual temporal analyses. All personal identifiers have been removed, and subjects are represented by coded IDs only. Files Included:- Main dataset file (.xlsx / .csv)- Variable legend / data dictionary Usage Notes:The dataset is provided to ensure transparency, reproducibility, and reuse for academic research purposes. Data should be interpreted in conjunction with the associated publication. Keywords:CRPS, Complex Regional Pain Syndrome, PIEZO1, biomarker, pain, mechanotransduction, neridronate, inflammation, rheumatology.