Research progress on electroacupuncture treatment for ischemic stroke： insights from multiple cell death mechanisms

Electroacupuncture， as an effective treatment for ischemic stroke， significantly improves patients’ prognosis and functional recovery. However， its underlying mechanisms of action have not been fully elucidated. This paper reviews and summarizes researches on electroacupuncture in regulating ischemic stroke based on multiple cell death mechanisms， detailing the progress in understanding how electroacupuncture inhibits apoptosis， modulates autophagy， suppresses pyroptosis， ameliorates ferroptosis， and regulates necroptosis. These cell death mechanisms form a complex network of interactions that collectively contribute to the onset and progression of ischemic stroke. Furthermore， this paper analyzes the limitations of current research and proposes future directions， providing a theoretical foundation for further exploration of the molecular mechanisms of electroacupuncture in treating ischemic stroke and the development of innovative therapeutic strategies.