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Chromatin remodeling in the aging genome of Drosophila

NIAID Data Ecosystem2026-03-08 收录

衰老表观遗传学

果蝇染色质重塑

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE22438 数据链接链接失效反馈

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资源简介：

ChIP-chip data for activation and repressive marks collected from 10 and 40 day old dmel heads h3k4, RNA polymerase, h3k36, h3k9me3, and hp1 Ips and input in 10day and 40day old adult fly heads

应用场景：

创建时间：

2015-07-08

DNA甲基化动态

衰老表观遗传学

DNA methylation levels in whole blood measured over a ten years follow up in an elderly birth cohort of 86 samples Overall design: For each sample, whole blood was drawn in year 1997 and in year 2007

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Bulk Omni-ATAC-seq in young (2 months) and aged (22-24 months) mice across 23 cell-types. Bulk Omni-ATAC-seq in young (2 months) and aged (22-24 months) mice across 23 cell-types

衰老表观遗传学

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To understand how age rewires the chromatin accessibility landscape, we molecularly profiled 23 purified cell types from 11 tissues and organs by assessing the cumulative signature of 15-25 young and

NIAID Data Ecosystem50

Additional file 6: of Genotype effects contribute to variation in longitudinal methylome patterns in older people

衰老表观遗传学

甲基化数量性状位点

Table S5. Four hundred thirty-six SNPs with genome-wide significant (P < 5 × 10−8) effects on the random slope of 343 rsCpGs. (CSV 27 kb)

NIAID Data Ecosystem50

Genome wide DNA methylation changes with age in disease free human skeletal muscle. Homo sapiens

DNA甲基化衰老

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A decline in skeletal muscle mass and function with aging is well recognized, but remains poorly characterized at the molecular level. Here we report for the first time a genome-wide study of DNA meth

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DNMT1 drives 4D genome rewiring during oncogene induced senescence. DNMT1 drives 4D genome rewiring during oncogene induced senescence

衰老表观遗传学

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While, transcriptional and epigenetic changes associated senescence processes are well studied, the 3D chromatin changes associated with it remains elusive. In this study, we have generated genome wid

NIAID Data Ecosystem50

Chromatin remodeling in the aging genome of Drosophila

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