CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE COMPLEXED WITH HP4A, THE TWO-SUBSTRATE-MIMICKING INHIBITOR

Protein Data Bank Japan2023-08-30 更新2026-03-21 收录

抗菌药物靶点

抑制剂复合物

数据链接：

https://pdbj.org/mine/summary/1ex8 数据链接链接失效反馈

官方服务：

资源简介：

CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE COMPLEXED WITH HP4A, THE TWO-SUBSTRATE-MIMICKING INHIBITOR Descriptor: 6-(ADENOSINE TETRAPHOSPHATE-METHYL)-7,8-DIHYDROPTERIN, 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, CHLORIDE ION, ... Authors: Blaszczyk, J, Ji, X. Deposit date: 2000-05-01 Release date: 2001-05-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: synthesis and biochemical and crystallographic studies. J.Med.Chem., 44, 2001

与双底物模拟抑制剂HP4A结合的6-羟甲基-7,8-二氢蝶呤焦磷酸激酶（6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase）的晶体结构描述符：6-(四磷酸腺苷-甲基)-7,8-二氢蝶呤、6-羟甲基-7,8-二氢蝶呤焦磷酸激酶、氯离子等作者：Blaszczyk, J、Ji, X. 存档日期：2000-05-01 发布日期：2001-05-01 最后修改日期：2023-08-30 实验方法：X射线衍射（分辨率1.85埃）引用文献：《6-羟甲基-7,8-二氢蝶呤焦磷酸激酶的双底物类似物抑制剂：合成及生化与晶体学研究》，《药物化学杂志》（J.Med.Chem.），第44卷，2001年

创建时间：

2000-05-01

CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE COMPLEXED WITH HP4A, THE TWO-SUBSTRATE-MIMICKING INHIBITOR

资源简介：

相关数据集