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Tipifarnib inhibits HRAS-driven dedifferentiated thyroid cancers: Adaptive responses and acquired mutations in Nf1 and Gnas are dirivers of resistance

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE112476
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Affymetric arrays were performed on thyroid samples collected from GEMMs: Cre-negative, Tpo-cre;HrasG12V (Homozygous), Tpo-cre;HrasG12V,p53f/f (PDTC), Tpo-cre;HrasG12V,p53f/f (ATC) Thyroids and tumor-bearing thyroid glands were isolated from various mouse models at baseline
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2019-02-11
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