Steady-state kinetic parameters for cleavage of Aβ1–40 and off-target peptides by NEP G399V and NEP G714K.
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*the best fit values of kcat and KM were determined by non-linear regression of activity data using the Michaelis-Menten equation. Values are quoted ± the average standard error generated from non-linear regression of data from two independent experiments.#the fold-change in kcat/KM is the ratio of the wild-type NEP kcat/KM to that of the NEP mutant.
创建时间：
2015-12-02
